Sleep quality and pain
Conditions
Interventions
Esketamine group:At induction of anesthesia, a loading dose of esketamine 0.5 mg/kg was injected intravenously, followed by continuous pumping at 0.1 mg·kg-1·h-1 to the suture skin
an intravenous analgesic pump was connected before leaving the operating room, and the dosing regimen for the pump was: esketamine 50 mg and sufentanil 1.5 ug·kg-1 (up to 150 ug) diluted to 100 ml wit
Control group:The analgesic pump was programmed to automatically press and measure 0.5 ml of 0.5 ml, locking the pump. Analgesic pump dosing regimen: sufentanil 2 ug/kg (maximum 150 ug) diluted with s
Sponsors
The Second Affiliated Hospital of Shandong First Medical University
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients who volunteered to participate in this trial, aged 65-80 years; ASA classification I-III, scheduled for elective lumbar spine surgery under general anesthesia.
Exclusion criteria
Exclusion criteria: Unscheduled or emergency surgery; cardiac insufficiency or severe lung disease (type I or II expiratory failure); severe hepatic or renal dysfunction (Child-Pugh class C, need for renal replacement therapy); comorbid psychiatric disorders, cognitive abnormalities, long-term use of antipsychotics, or drug addiction; allergies or contraindications to medications used in the study; illiteracy or inability to comprehend the scales in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Insomnia Severity Index;Portable Sleep Apnea Detector;Pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pittsburgh sleep quality index;Quality of Recovery; | — |
Countries
China
Contacts
Public ContactMen Yongjiao
The Second Affiliated Hospital of Shandong First Medical University
Outcome results
None listed