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A clinical study of chloroprocaine at 90% effective concentration (ED90) for epidural labor analgesia

A clinical study of chloroprocaine at 90% effective concentration (ED90) for epidural labor analgesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500103057
Enrollment
Unknown
Registered
2025-05-23
Start date
2025-06-01
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Labor analgesia

Interventions

A group:Chloroprocaine at 0.4% concentration
B group:Chloroprocaine at 0.6% concentration
C group:Chloroprocaine at 0.8% concentration
Dgroup:Chloroprocaine at 1.0% concentration

Sponsors

Women's Hospital School of Medicine Zhejiang University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Healthy full-term singleton primigravida; 2-5 cm dilatation, 50 mm pain score on the visual analog scale for contraction pain; age 20-40 years; American Society of Anesthesiologists (ASA) class II; BMI 20-35 kg/m^2; and signed an informed consent form.

Exclusion criteria

Exclusion criteria: Contraindications to intrathecal anesthesia; comorbid pregnancy-related disorders (hypertension, diabetes mellitus, mild or severe preeclampsia, placental abruption, placenta previa, etc.); cardiopulmonary disease; hepatic or renal disease; history of chronic pain; history of narcotic drug abuse; fetal anomalies (malformations, stillbirth, etc.); psychiatric disorders; allergy to local anesthetics; refusal to participate in the study.

Design outcomes

Primary

MeasureTime frame
Pain score;

Countries

China

Contacts

Public ContactChen Xinzhong

Women's Hospital School of Medicine Zhejiang University

daishaobing@126.com+86 187 5820 3215

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026