Postoperative delirium
Conditions
Interventions
Hypozincemia group:None
None hypozincemia group:None
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Age >= 18 years old; (2) Patients scheduled for elective cardiac surgery under general anesthesia with tracheal intubation and extracorporeal circulation; (3) ASA grades II to IV; (4) Proficient in communicating in Chinese; (5) Patients or their family members have agreed to participate in this study and have signed the informed consent form;
Exclusion criteria
Exclusion criteria: (1) Patients with previous mental/neurological disorders, such as depression, severe central nervous system inhibition, schizophrenia, epilepsy, Parkinson's disease or Alzheimer's disease, etc.; (2) Patients who cannot undergo cognitive tests due to hearing impairment, visual impairment or dementia; (3) Preoperative cognitive dysfunction, defined as a total score of MMSE lower than the cutoff value corresponding to the educational level: illiterate 6 years) <= 23 points; (4) Patients who routinely used psychotropic drugs, opioid drugs, etc. before the operation; (5) Patients with preoperative conditions such as delirium, coma or dementia that affect normal communication; (6) Patients with a history of alcohol abuse or withdrawal in the past 6 months; (7) Patients taking drugs containing related trace elements (such as oral zinc supplements); (8) Patients currently participating in other clinical trials; (9) Patients scheduled to undergo 2 surgeries within 7 days after the operation;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of postoperative delirium;Duration of postoperative delirium;Postoperative complications; | — |
Countries
China
Contacts
Public ContactChen Lijian
The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed