Dry eye, ocular surface diseases
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Voluntarily participate in this clinical study and sign the informed consent form;2.Diagnosed with lymphoma;3.Age >= 18 years, regardless of gender;4.Undergoing antitumor therapy;5.Have ophthalmic examination records.
Exclusion criteria
Exclusion criteria: 1.Inability or refusal to undergo follow-up due to any reason;2.Pre-existing severe ophthalmic comorbidities before treatment;3.Active infectious ocular inflammation;4.Abnormal eyelid anatomy leading to incomplete eyelid closure (including entropion and ectropion);5.Intraocular surgery within the past 6 months;6.Any condition (including language barriers) that, in the investigator's judgment, may pose significant risks, confound study results, or substantially interfere with the subject's participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ocular Surface Disease Index Questionnaire Score;Pain Numerical Rating Scale Score;Tear break-up time,TBUT;Corneal fluorescein staining score;Conjunctival lissamine green staining score;Schirmer I test;Conjunctival redness evaluation;Lid parallel conjunctival folds score;Detection of tear inflammatory factors;Conjunctival impression cytology;Meibomian gland secretion quality;Grading of meibomian gland duct obstruction;Meibomian gland secretory capacity classification;Fundus condition; | — |
Countries
China
Contacts
Beijing Tongren Hospital, Capital Medical University