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Changes in ocular clinical characteristics of lymphoma patients before and after antitumor therapy

Changes in ocular clinical characteristics of lymphoma patients before and after antitumor therapy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500103016
Enrollment
Unknown
Registered
2025-05-22
Start date
2025-06-01
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry eye, ocular surface diseases

Interventions

Lymphoma patients receiving antitumor therapy:None

Sponsors

Beijing Tongren Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Voluntarily participate in this clinical study and sign the informed consent form;2.Diagnosed with lymphoma;3.Age >= 18 years, regardless of gender;4.Undergoing antitumor therapy;5.Have ophthalmic examination records.

Exclusion criteria

Exclusion criteria: 1.Inability or refusal to undergo follow-up due to any reason;2.Pre-existing severe ophthalmic comorbidities before treatment;3.Active infectious ocular inflammation;4.Abnormal eyelid anatomy leading to incomplete eyelid closure (including entropion and ectropion);5.Intraocular surgery within the past 6 months;6.Any condition (including language barriers) that, in the investigator's judgment, may pose significant risks, confound study results, or substantially interfere with the subject's participation.

Design outcomes

Primary

MeasureTime frame
Ocular Surface Disease Index Questionnaire Score;Pain Numerical Rating Scale Score;Tear break-up time,TBUT;Corneal fluorescein staining score;Conjunctival lissamine green staining score;Schirmer I test;Conjunctival redness evaluation;Lid parallel conjunctival folds score;Detection of tear inflammatory factors;Conjunctival impression cytology;Meibomian gland secretion quality;Grading of meibomian gland duct obstruction;Meibomian gland secretory capacity classification;Fundus condition;

Countries

China

Contacts

Public ContactYan He

Beijing Tongren Hospital, Capital Medical University

dryanhe@163.com+86 178 1209 1348

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026