Sepsis
Conditions
Interventions
The patients with infection but not sepsis:None
Sponsors
Shanghai Children’ s Medical Center
Eligibility
Sex/Gender
All
Age
28 Days to 18 Years
Inclusion criteria
Inclusion criteria: - Septic children 28 days to 18 years old. - Meeting the diagnostic criteria for sepsis. - The guardian or the patient signs the informed consent form for the collection of biological samples, cooperates with the study, and provides the required feces (2 samples). During the clinical diagnosis and treatment process, 1 ml of blood sample is collected for the study.
Exclusion criteria
Exclusion criteria: - Children with chronic diseases and other serious diseases that affect gut microbiota homeostasis except for sepsis, such as diabetes mellitus, immunodeficiency, autoimmune diseases, inflammatory bowel disease, etc. - Children who have been on long-term antibiotic use or have experienced diarrhea within the past three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Microbial biomarker; | — |
Secondary
| Measure | Time frame |
|---|---|
| Microbial metabolites; | — |
Countries
China
Contacts
Public ContactXi Mo
Shanghai Children's Medical Center
Outcome results
None listed