Cognition impariment
Conditions
Interventions
Moderate exercise group without exercise habits:The subjects in this group were those who had no exercise training habits before enrollment. According to the individual VO2max level, the weekly exerci
Have exercise habits and maintain moderate exercise group:The subjects of this group were the people who had exercise habits before enrollment. According to the questionnaire survey, the total met val
Group with exercise habit and step up exercise:The subjects of this group were the people who had exercise habits before enrollment. According to the questionnaire survey, the total met value of weekl
Sponsors
The Second Affiliated Hospital of University of South China
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Healthy subjects: 1.18.5= 18 years and <= 40 years; 3. Physical and mental health; 4.The experimental compliance is good, and those who can participate in high-intensity sports after physical examination; 5. Patients or close relatives can fully understand the informed consent form, agree to participate in the study and sign the informed consent form; 6.Cognitive function was normal.
Exclusion criteria
Exclusion criteria: If any of the following criteria is met, the subject cannot be enrolled in the intervention study: 1. Participated in any intervention clinical research (including drug / device / biological agent test) within 3 months before enrollment; 2. History of major systemic diseases (to meet the current clinical significance), details are as follows: Diseases of circulatory system (such as coronary heart disease, hypertension above grade II, severe arrhythmia); Metabolic and endocrine diseases (diabetes, hyperthyroidism / hypothyroidism, etc.); urinary system diseases (chronic kidney disease stage 3 and above); Neurological diseases (epilepsy, stroke sequelae, etc.); Immune system abnormalities (primary / acquired immunodeficiency, autoimmune diseases); Other systemic diseases (blood system, respiratory system, psychiatric diseases, etc.); 3. Diagnosed with dementia or scored 400 ml) within 3 months before the test; 13.Those with motor system diseases, such as osteoarthritis and fracture, who are unable to complete motor tasks, or those with other system diseases that affect cognition and motor function; 14.Had undergone surgery within 3 months before the trial; Or planned surgical procedures during the study period; 15.Alcoholics or regular drinkers within 6 months before the test, i.e. drinking more than 14 units of alcohol per week (1 unit =360 ml beer or 45 ml spirits with 40% alcohol or 150 ml wine); Or unwilling to stop drinking alcohol or use any alcohol containing products during the test; Or positive alcohol breath test result (> 0.0 mg/100 ml); 16.Patients with cardiac pacemakers, cochlear implants, steel nails, steel plates, or claustrophobia who are not suitable for magnetic resonance examination. 17.Those who have used any drug within 30 days before the test; The 18.Those who cannot be
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fluid Intelligence;Numeric Memory score;Cognitive function;Cardiopulmonary exercise; | — |
Secondary
| Measure | Time frame |
|---|---|
| Laboratory test indicators; | — |
Countries
China
Contacts
Public ContactJianping Wang
The Second Affiliated Hospital of Nanhua University
Outcome results
None listed