Parkinson's disease
Conditions
Interventions
PD group with T2DM:None
PD group without T2DM:None
Sponsors
The First Affiliated Hospital of University of Science and Technology of China
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Parkinson's disease patients with or without T2DM; 2) No gender limitation, age 18-80 (including 18 and 80 years old);
Exclusion criteria
Exclusion criteria: 1) a history of dementia; 2) a history of mental disorders or current treatment for mental illnesses, such as taking anxiolytics, antidepressants, mood stabilizers, antipsychotics and other drugs that may interfere with the assessment; 3) a history of drug abuse or dependence; 4) pregnant women; 5) severe physical illnesses that may interfere with the assessment; 6) contraindication to MRI scan; 7) declining to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PD-CRS scores;Ktrans values and Vp values in different brain regions;The volumes of specific brain regions and cortical thickness; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum levels of soluble ICAM-1?VCAM-1 and S100B; | — |
Countries
China
Contacts
Public ContactJieping Lu
The First Affiliated Hospital of University of Science and Technology of China
Outcome results
None listed