Retinopathy of prematurity
Conditions
Interventions
Standard dose-Low dose group:One drop of the standard-dose combined topiramide (approximately 30 µL) was screened for the first time, and after a 1 to 2-week washout period, a small dose of combined t
Low dose-Standard dose group:The first screening of low-dose combined topiramide (15 µL), after a 1 to 2-week washout period, a drop of the standard dose of combined topiramide (approximately 30 µL) w
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Preterm infants with gestational age <32 weeks or birth weight <2000g were screened for retinopathy of prematurity during hospitalization.
Exclusion criteria
Exclusion criteria: None
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pupil diameter; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate;Blood pressure(SBPDBPMBP);Blood oxygen saturation;Intestinal tissue oxygen saturation;Local and systemic adverse events; | — |
Countries
China
Contacts
Public ContactHao Qingfei
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed