rare (hereditary/acquired) bleeding disorders
Conditions
Interventions
Observation group:None
Sponsors
The Fourth Medical Center of PLA General Hospital, Beijing, China
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients hospitalized in our center from 2010 to the present (and in the future), as well as family members of patients with suspected hereditary disorders (no restrictions on age or gender). Conditions of Interest Include (but Are Not Limited to): Hereditary/acquired coagulation factor deficiencies (e.g., fibrinogen, prothrombin, FV, FVII, FX, FXI, FXIII deficiencies, etc.); Hereditary platelet function disorders; Hereditary von Willebrand disease.
Exclusion criteria
Exclusion criteria: Patients with the following conditions will be excluded: Classic hemophilia A/B (to avoid confounding factors in rare disorder studies); Liver dysfunction-associated coagulation abnormalities; Coagulopathy secondary to underlying conditions (e.g., hemorrhage, infection, malignancy); Drug-induced coagulation disorders (e.g., anticoagulant therapy).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prothrombin time;Activated partial thromboplastin time;fibrinogen;Coagulation factor activity;gene test;TEG test; | — |
Countries
China
Contacts
Public ContactChen Guanyi
The Fourth Medical Center of PLA General Hospital, Beijing, China
Outcome results
None listed