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A Study on the Sedation and Analgesic Effects of Esketamine Combined with Dexmedetomidine in DISE Examinaton for OSAS Patients

A Study on the Sedation and Analgesic Effects of Esketamine Combined with Dexmedetomidine in DISE Examinaton for OSAS Patients

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500102931
Enrollment
Unknown
Registered
2025-05-21
Start date
2025-05-29
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive sleep apnea syndrome

Interventions

Experimental group:ketamine combined with dexmedetomidine
Control group:Propofol combined with midazolam

Sponsors

Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients with OSAS; 2. American Society of Anesthesiologists (ASA) grade I.~II; 3. The age of the patient is 18~65 years old; 4. Patient informed consent.

Exclusion criteria

Exclusion criteria: 1. History of upper respiratory tract surgery; 2. Those who are allergic to the drugs used in the examination; 3. Have a history of mental illness; 4. Pregnant or lactating women

Design outcomes

Primary

MeasureTime frame
EEG Bispectral Index (BIS);

Secondary

MeasureTime frame
Changes in vital signs during examination;Electroencephalogram during the examination;Check the medication during the process;Adverse events;Evaluation of analgesic efficacy;

Countries

China

Contacts

Public ContactJia Yan

Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine

mzkyanj@163.com+86 18019790783

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 15, 2026