Vulvar intraepithelial neoplasia(VIN),Vulvar condyloma acuminata,Lichen sclerosus of the vulva
Conditions
Interventions
The control group (local cooling group):None
The study group (the group with tetracaine gel externally applied to the vulva):None
Sponsors
The international peace maternity and child health hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Clinically diagnosed vulvar lesions: vulvar condyloma acuminata, vulvar intraepithelial neoplasia, vulvar lichen sclerosus, with indications for photodynamic therapy; 2.The age ranges from 18 to 70 years old; 3.The patient has completed at least one standardized vulvar photodynamic therapy session, truthfully provided pain feedback, and undergone subsequent follow-ups; 4.The medical records are complete, including detailed treatment records, pain assessment using the Visual Analogue Score (VAS score), and records of adverse reactions.
Exclusion criteria
Exclusion criteria: 1.Combined with severe systemic critical illnesses such as severe cardiovascular and cerebrovascular diseases, hepatic and renal insufficiency, malignant tumors, etc., which affect pain perception and drug metabolism; 2.Known to be allergic to tetracaine, allergic to excitation light sources such as red light, or with a history of allergic constitution; 3.Women during pregnancy and lactation period; 4.Suffering from mental illness or cognitive impairment and unable to cooperate with the pain assessment and the research process; 5.Patients with severe damage and infection at the site of vulvar lesions, which may interfere with the absorption of drugs, affect the cooling effect of the air cooler, and impact the accuracy of pain assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Self-Rating Anxiety Scale,SAS;Dermatology Life Quality Index,DLQI;Visual Analogue Scale,VAS; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence rate of adverse reactions, covering local adverse reactions (such as redness, swelling, itching, etc.) and systemic adverse reactions (such as dizziness, nausea, etc.); track the treatme; | — |
Countries
China
Contacts
Public ContactLei Bao
The international peace maternity and child health hospital
Outcome results
None listed