Gastric wall defects resulting from endoscopic treatment for gastric lesions—including early-stage cancer, precancerous lesions, and submucosal tumors—with partial or complete resection of the muscularis propria
Conditions
Interventions
Congtrol group:Metal clip related closure
Test group:Endoscopic Hand-Suturing
Sponsors
Peking University First Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Gastric lesions that are deemed endoscopically resectable upon evaluation; 2. Underwent endoscopic surgery with partial or complete resection of the muscularis propria; 3. Age between 18 and 75 years (inclusive); 4. Preoperative ECOG performance status score of 0–1.
Exclusion criteria
Exclusion criteria: 1. Lesions with confirmed lymph node metastasis; 2. Poor general condition or inability to tolerate endoscopic surgery; 3. Patients with coagulation disorders (platelet count 2) or on anticoagulant therapy prior to correction of coagulation status; 4. Patients who have received radiotherapy to the surgical site; 5. Lesions that cannot be completely resected endoscopically; 6. Defects adjacent to or involving the cardia or pylorus; 7. Patients who refuse surgery or decline participation in the clinical trial; 8. Any other clinical conditions deemed inappropriate for trial participation by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sustained closure rate of postoperative defects; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative delayed bleeding;Postoperative delayed perforation;Success rate of postoperative defect closure;Other postoperative adverse events;Suturing time; | — |
Countries
China
Contacts
Public ContactShibo Song
Peking University First Hospital
Outcome results
None listed