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Study on the brain mechanism of Tai Chi exercise synchronous transcranial direct current stimulation (tDCS) to improve respiratory function after stroke

Study on the brain mechanism of Tai Chi exercise synchronous transcranial direct current stimulation (tDCS) to improve respiratory function after stroke

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500102889
Enrollment
Unknown
Registered
2025-05-21
Start date
2023-11-22
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory Dysfunction in Stroke

Interventions

Tai Chi + tDCS Group:Undergoing Tai Chi while simultaneously receiving tDCS stimulation.
Tai Chi + tDCS Sham Stimulation Group:Undergoing Tai Chi while simultaneously receiving sham tDCS stimulation.
tDCS + Walking Group:Walking in a designated area while receiving tDCS stimulation.

Sponsors

Guangdong Clifford Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Age between 30 and 75 years; 2.Diagnosed with cerebrovascular disease according to the 2019 "Chinese Diagnostic Criteria for Major Types of Cerebrovascular Diseases" and confirmed by cranial CT or MRI; 3.Maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP) are less than 60% of predicted values; 4.Standing balance >= grade 1, and walking function Holden grade >=2 (can walk on flat ground for 20 minutes under supervision); 5.No auditory comprehension impairment, able to follow simple commands; 6.No history of chronic obstructive pulmonary disease (COPD) or other respiratory diseases, and no coronary heart disease or other cardiac diseases; 7.No metallic implants in the brain or body.

Exclusion criteria

Exclusion criteria: 1. Patients with neurological diseases other than stroke; 2. Contraindications for MRI examination; 3. Contraindications for tDCS (e.g., metallic implants in the head, electronic pacemakers, history of traumatic brain injury, epilepsy, or cranial defects); 4. Patients with severe heart, lung, or kidney diseases; 5. Patients with severe cognitive or psychiatric disorders that prevent cooperation; 6. History of lung surgery or recent severe respiratory difficulties, chest tightness, or shortness of breath due to lung infections; 7. Patients with severe facial asymmetry that affects the results of respiratory function tests.

Design outcomes

Primary

MeasureTime frame
FEV1;FCV;FEV1/FVC%;MVV;MIP;

Secondary

MeasureTime frame
6 minutes walking distance;Berg Balance;Lower limb function;Modified Barthel Index (MBI) ;Brain function;

Countries

China

Contacts

Public ContactZhang Xinting

Guangdong Clifford Hospital

35940648@qq.com+86 136 3246 0966

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026