Advanced solid malignancies
Conditions
Interventions
Experimental group:None
the control group:None
Sponsors
The Second Affiliated Hospital of the Army Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Informed consent has been signed and, in the judgment of the investigator, the patient is able to comply with the study protocol and sign a written informed consent. 2.the advanced malignant tumors (solid tumors of the non-small-cell lung carcinoma, stomach, breast, urinary system, etc.) were diagnosed by histopathology. 3.the stage IV according to the eighth edition of IASLC; 4.PS 0-2, the expected survival > 3 months; 5.the age of 18-75 years; 6.no contraindication to treatment with immune checkpoint inhibitors; 7.Complete multi-omics testing and data collection. 8.Complete cardiac MRI examination and myocardial injury markers.
Exclusion criteria
Exclusion criteria: 1.the patients' compliance was poor, which violated the rules of the trial; 2.the patients with severe dysfunction of vital organs (heart, liver and kidney; 3.the patients with other malignant tumors; 4.the researchers considered that the patients should not participate in other conditions of the trial;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| progression-free survival;Objective Response Rate; | — |
Countries
China
Contacts
Public ContactSun Jianguo
The Second Affiliated Hospital of the Army Medical University
Outcome results
None listed