Spinal metastatic tumor
Conditions
Interventions
3D-printed barriers group:3D-printed barrier
bone cement group:bone cement
Sponsors
Xi'an Jiaotong University Second Affiliated Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-80 years; 2. Pathologically diagnosed with spinal metastasis; 3. Imaging shows spinal cord compression and vertebral mass, with symptoms consistent with imaging findings; 4. No concomitant conditions affecting spinal cord function, such as traumatic fractures or severe lumbar degenerative diseases; 5. Expected survival time of more than 6 months; 6. General condition allows for tolerance of surgery; 7. Tomita score between 4-7, candidate for marginal or intralesional tumor resection, palliative decompression, and stabilization surgery; 8. SINS score > 7, requiring surgery for stabilization; 9. Willing to participate and signs the informed consent form;
Exclusion criteria
Exclusion criteria: 1. History of spinal or spinal cord injury or previous spinal surgery; 2. Patients with primary spinal tumors or solitary bone metastasis requiring radical surgery; 3. Patients undergoing conservative treatment; 4. Combined with brain metastases; 5. Combined with cranial trauma, central nervous system diseases, etc; 6. Death within 6 months post-surgery; 7. Frankel classification Grade A; 8. Patients in poor general condition who cannot tolerate surgery; 9. Patients unable to cooperate with completing the assessment;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to tumor recurrence causing spinal cord compression;Surgical safety assessment (bleeding volume);Postoperative functional evaluation (VAS);Evaluation of the postoperative position of the spacer and cement, and the extent of bone destruction;Postoperative functional evaluation (JOA);Evaluation of postoperative bone tumor progression and spinal canal volume;Evaluation of postoperative bone tumor progression and extent of bone destruction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Surgical safety assessment (surgical duration);Surgical safety assessment (number of fluoroscopy); | — |
Countries
China
Contacts
Public ContactZhao Bo
Xi'an Jiaotong University Second Affiliated Hospital
Outcome results
None listed