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Effect of individualized inspired oxygen concentration during one-lung ventilation on postoperative pulmonary complications in patients undergoing pneumonectomy: a prospective randomized controlled trial

Effect of individualized inspired oxygen concentration during one-lung ventilation on postoperative pulmonary complications in patients undergoing pneumonectomy: a prospective randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500102870
Enrollment
Unknown
Registered
2025-05-21
Start date
2025-06-01
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung surgery

Interventions

Sponsors

The First Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients who intend to electively undergo thoracoscopic partial lung resection under general anesthesia; 2. Age> = 18 years, gender is not limited; 3. American Society of Anesthesiologists (ASA) grade I-IV; 4. Know, agree to participate in the trial and sign a written informed consent form.

Exclusion criteria

Exclusion criteria: 1. History of severe pulmonary diseases, such as chronic obstructive pulmonary disease (GOLD grade 3 - 4), severe asthma, thoracic and spinal deformities, pleural effusion, pneumothorax, history of previous lung surgery, etc., which affect lung compliance; 2. Severe cardiac (NYHA Class III or IV), liver (Child-Pugh 10 – 15 points), renal (renal replacement therapy), hematopoietic system (leukemia) disease; 3. History of previous lung surgery; 4. History of upper respiratory tract infection within two weeks before surgery; 5. Participated in other clinical studies in the past 3 months.

Design outcomes

Primary

MeasureTime frame
Postoperative pulmonary complications;

Secondary

MeasureTime frame
Oxygenation index;Mechanical ventilation parameters;The incidence of intraoperative hypoxemia;

Countries

China

Contacts

Public ContactLijian Chen

The First Affiliated Hospital of Anhui Medical University

chenlijian77@126.com+86 139 6669 9467

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026