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Exploratory study on the efficacy and safety of bupivacaine liposomes for postoperative analgesia in elderly hip fracture patients

Exploratory study on the efficacy and safety of bupivacaine liposomes for postoperative analgesia in elderly hip fracture patients

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500102867
Enrollment
Unknown
Registered
2025-05-21
Start date
2025-06-30
Completion date
Unknown
Last updated
2026-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip Fracture

Interventions

Bupivacaine group :Bupivacaine liposome infiltration anesthesia
Control group:Without bupivacaine liposome infiltration anesthesia

Sponsors

Beijing Jishuitan Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Trauma orthopedics plans to perform hip fracture surgery; 2. ASA grade I~ III; 3. Not less than 65 years old, gender not limited; 4. Capable of language expression or reading, able to independently or with the help of a physician understand and complete survey questionnaires, and agree to participate in the study.

Exclusion criteria

Exclusion criteria: 1. Patients with combined mental system disorders and cognitive dysfunction; 2. Combined sensory disorders such as hyperalgesia or other physical pain that affects postoperative pain assessment; 3. Allergy to bupivacaine or other amide local anesthetics, as well as severe liver or renal dysfunction; 4. Patients with any other factors that are not suitable for participating in this trial. There are mental illnesses, consciousness disorders, and communication barriers present.

Design outcomes

Primary

MeasureTime frame
VAS score ;

Secondary

MeasureTime frame
Time from operation to discharge (hour);Complication ; Sleep quality assessment ;Dosage of Tramadol ;Postoperative ambulation time ;Patient pain satisfaction score at 72 hours after surgery ;Number of compressions of analgesic pump ;The total consumption of opioid drugs from the end of surgery to 72 hours after surgery;The incidence of delirium within 3 days after surgery;

Countries

China

Contacts

Public ContactLi Ting

Beijing Jishuitan Hospital, Capital Medical University

jstliting@163.com+86 139 1008 4939

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 20, 2026