Traumatic brain injury
Conditions
Interventions
Control group:During the operation, Ringer's solution lactate was used for fluid replacement
Experimental group:During the operation, sodium bicarbonate Ringer's solution was used for volume therapy
Sponsors
Chinese People's Liberation Army Northern Theater Command General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing non-penetrating traumatic brain injury (TBI) surgery who were admitted to the hospital within 24 hours; 2. Age: 18-64 years old 3. Body mass index (BMI) < 28kg·m-2; 4. American Society of Anesthesiologists (ASA) classification II - IV
Exclusion criteria
Exclusion criteria: 1. Severe functional insufficiency of important organs such as the heart and lungs; 2. Malignant tumors or aneurysms; 3. There were already mental disorders such as cognitive dysfunction before the injury; 4. Patients with infection, liver dysfunction and kidney dysfunction before admission; 5. Refuse to test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Creatinine clearance rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood potassium concentration;Blood potassium concentration;Oxygenation index; | — |
Countries
China
Contacts
Public ContactLi Lin
Chinese People's Liberation Army Northern Theater Command General Hospital
Outcome results
None listed