Neck Wrinkles
Conditions
Interventions
Experimental group:The experimental group received Rinkles?, a cross-linked sodium hyaluronate (HA) gel containing 15 mg/mL of cross-linked sodium hyaluronate, 3 mg/mL of lidocaine hydrochloride, phos
The control group:The control group received a non-cross-linked HA compound containing 5.00 mg/mL of sodium hyaluronate, 2.00 mg/mL of L-carnosine, 0.10 mg/mL of glycine, 0.10 mg/mL of alanine, 0.20 m
Sponsors
The First Affiliated Hospital of Xi 'an Jiaotong University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. 18 =2 for neck wrinkles judged by the researcher; 4. Subjects who voluntarily sign informed consent and have good compliance; 5. The investigator evaluated the subjects deemed suitable for inclusion.
Exclusion criteria
Exclusion criteria: 1. Patients with serious systemic diseases, such as myocardial infarction, stroke, cancer, connective tissue diseases (such as scleroderma, systemic lupus erythematosus), systemic infections, diabetes, blood and lacrimal diseases, etc., and those who may require immunosuppressive drugs during the trial; 2. History of neck skin disease, cicatricial constitution or foreign body granuloma; 3. Pregnant or lactating women, who have a pregnancy plan during the test; 4. People with abnormal spirits; 5. Have a history of allergy, allergic to narcotic drugs; 6. Subjects with severe cardiac or renal dysfunction (aspartate aminotransferase AST or alanine aminotransferase ALT exceeding 3 times the upper limit of the normal range; Severe kidney disease; Serum creatinine > 2.0mg/dL or >=176.8µmol/L); 7. Patients with abnormal hypersensitivity; 8. Patients with abnormal coagulation function and clinical significance; 9. Participants in clinical trials of other drugs or medical devices within six months; 10. No history of submental chemical exfoliation, laser or scar removal, no history of submental skin relaxation treatment within six months; 11. Subjects that the investigator considers inappropriate to participate in this clinical validation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| llergan Transverse Neck Lines Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| llergan Transverse Neck Lines Scale;Global Beauty Results Satisfaction;Pain evaluation; | — |
Countries
China
Contacts
Public ContactMaoguo Shu
The First Affiliated Hospital of Xi'an Jiao Tong University
Outcome results
None listed