Respiratory Pathogens on the Dentures
Conditions
Interventions
Intervention ARM Group (ultrasonic and chemical cleaning):In the intervention arm participants will receive a portable and lightweight ultrasonic cleaner (Lohas ultrasonic cleaner GXZ UC01, Lohas Tech
Control ARM Group (conventional mechanical and chemical cleaning):To standardise the conventional mechanical brushing approach all participants will receive a commercially available denture brush (GUM
Sponsors
Faculty of Dentistry, The University of Hong Kong
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Participants will be adults who are wearing a complete or extensive partial maxillary or mandibular denture for at least 1 year and a maximum of 3 years. 2. Dentures fabricated with heat-polymerized acrylic resin and biofilm present on denture surfaces (as assessed by the semi-automated planimetric method). 3. Older adults of either sex and at least 60-year-old. 4. Ability to understand and provide informed consent [as assessed by Mini-Mental State Examination, mild and no cognitive impairment (scores=18) will be included] . 5. The denture has adequate retention and stability (as assessed by the Kapur index, retention scores >=2 and stability scores >=1 will be included).
Exclusion criteria
Exclusion criteria: 1. Participants have an indwelling nasogastric feeding tube or percutaneous endoscopic gastrostomy (unable to eat and drink normally). 2. Smoker (including e-cigarettes and tobacco chewing). 3. Participants are diagnosed with acquired immune deficiency syndrome, uncontrolled diabetes mellitus, anaemia, xerostomia, or immunosuppression. 4. Use of steroid treatment, antibiotics/antifungal medication, or undergoing radio- or chemotherapy within the past 4 weeks before recruitment and during follow-up. 5. The denture has been relined, repaired, or retained using denture adhesive products. 6. The denture with partially or completely ill-fitting/fracture. 7. Participants who are wearing dentures during meals only.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The prevalence (persistence + +, acquisition - +, transience/loss + -, and absence - -), abundance, and microbiome-based index (ORPI) of the respiratory pathogens or microbial index of pathogenic bacteria (MIP); | — |
Secondary
| Measure | Time frame |
|---|---|
| Denture plaque area coverage assessment;Prevalence of denture stomatitis;Patient-Reported Outcome Measures (PROMs); | — |
Countries
China
Contacts
Public ContactLim Tong Wah
Faculty of Dentistry, The University of Hong Kong
Outcome results
None listed