Iridocorneal endothelial (ICE) syndrome is a group of ocular disorders characterized by abnormal proliferation of corneal endothelial cells, structural abnormalities of the iris, cornea, and anterior chamber angle. Clinical manifestations may include corneal edema, pupil distortion and ectropion, iris stromal atrophy, iris pigment nevus, and peripheral anterior synechiae of the iris. These patholo
Conditions
Interventions
Normal eye group:None
ICE syndrome group:None
Fuchs corneal endothelial dystrophy group:None
A-R syndrome group:None
Posterior pleomorphic corneal endothelial dystrophy group:None
Sponsors
Eye Hospital, Wenzhou Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patients diagnosed with iridocorneal endothelial (ICE) syndrome, progressive iris atrophy (PIA), Chandler syndrome (CS), or Cogan-Reese syndrome (CRS) at the outpatient or inpatient departments of the Eye Hospital of Wenzhou Medical University between January 2014 and December 2024 were included. 2.Patients diagnosed with Fuchs endothelial dystrophy at the outpatient or inpatient departments of the Eye Hospital of Wenzhou Medical University between January 2014 and December 2024 were included. 3.Patients diagnosed withpolymorphous posterior corneal dystrophy at the outpatient or inpatient departments of the Eye Hospital of Wenzhou Medical University between January 2014 and December 2024 were included. 4.Patients diagnosed with Axenfeld-Rieger syndrome at the outpatient or inpatient departments of the Eye Hospital of Wenzhou Medical University between January 2014 and December 2024 were included. 5.Unilateral ocular trauma inpatients in the Ocular Trauma inpatient Department of the Eye Hospital of Wenzhou Medical University between January 2014 and December 2024 were included.
Exclusion criteria
Exclusion criteria: 1.Patients whose above-mentioned inclusion diagnosis was revised to other ocular disease diagnoses during follow-up. 2.Patients without anterior segment photographic imaging data. 3.Patients without detailed outpatient medical records.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Speciffcity;Sensitivity; | — |
Countries
China
Contacts
Public ContactYuanbo Liang
Eye Hospital, Wenzhou Medical University
Outcome results
None listed