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The Central Mechanisms of Drug and Transcranial Magnetic Stimulation in the Treatment of Chronic Insomnia Disorder: An Exploration Based on Clinical Imaging Techniques

The Central Mechanisms of Drug and Transcranial Magnetic Stimulation in the Treatment of Chronic Insomnia Disorder: An Exploration Based on Clinical Imaging Techniques

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500102804
Enrollment
Unknown
Registered
2025-05-20
Start date
2023-12-25
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic insomnia disorder

Interventions

Zopiclone treatment group:None
rTMS intervention combined with zopiclone group:rTMS intervention combined with zopiclone treatment

Sponsors

Xiangyang Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Select 100 patients aged 18-60 years who have a confirmed diagnosis of chronic insomnia disorder and are receiving treatment at the Neurology Department of Xiangyang Central Hospital. The patients should have a disease duration of at least 3 months, and the use of sedative-hypnotic medications should not exceed 4 times per week. 2.Primary school and above education level; 3.Right-hander; 4.No organic lesions were found in the head MR;

Exclusion criteria

Exclusion criteria: 1.Secondary insomnia caused by physical diseases, drugs and other reasons; 2.Pregnant and lactating women, alcohol or drug dependence, etc.; 3.MR examination taboos; 4.Those who refuse to sign the informed consent form for treatment;

Design outcomes

Primary

MeasureTime frame
Effectiveness of rTMS intervention combined with zopiclone in treating patients with chronic insomnia;

Secondary

MeasureTime frame
Neuroimaging markers of patients with chronic insomnia treated with rTMS intervention combined with zopiclone;

Countries

China

Contacts

Public ContactShang Furong

Xiangyang Central Hospital

sfrxy@sohu.com+86 13707272098

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026