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Performance testing of large language models for the diagnosis and management of cardiovascular disease: a development and validation study

Performance testing of large language models for the diagnosis and management of cardiovascular disease: a development and validation study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500102798
Enrollment
Unknown
Registered
2025-05-20
Start date
2025-05-31
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiovascular disease

Interventions

Control Group :Usual care according to clinical guidelines for the management of cardiovascular disease
Large Language Model Management Group:Management based on large language models management system based on cardiovascular disease guideline treatments Large model management group

Sponsors

Suzhou First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. patients aged 18 years and above; 2. clinical suspicion or diagnosis of cardiovascular disease; 3. complete patient examination data (e.g., electrocardiogram, ultrasound, CT, MRI, and biochemical indices); and 4. signing of informed consent. Medical Ethics Committee, People's Hospital 26 Yinhe 1st Road, Cebu City, China

Exclusion criteria

Exclusion criteria: 1. Patients with incomplete data, who do not meet diagnostic criteria, or who lack follow-up information; 2. Other complex systemic diseases (e.g., multiple organ failure, advanced cancer) with a history that interferes with diagnostic judgements made by the large language model; 3. Individuals with impaired consciousness, an inability to communicate normally, or any psychiatric condition; individuals who are unable to take care of themselves or who have difficulty with mobility; 4. Individuals with life expectancy < 12 months; 5. Individuals with abnormalities in lab tests and clinical manifestations that, in the judgement of the investigator, make them unsuitable for participation; 6. Individuals who do not wish to participate in the study and do not wish to change their current medication regimen.

Design outcomes

Primary

MeasureTime frame
sensitivities;specific;accuracy;Positive predictive value;Negative predictive value;receiver operating characteristic curve;Blood Pressure;heart rate toolbar.listen;LVEF;knowledge level test;BMI;psychological condition;sleep quality;lifestyle;cognitive function;

Secondary

MeasureTime frame
usability evaluation;MACCEs;

Countries

China

Contacts

Public ContactBowen Zhou

Suzhou First People's Hospital

junw1214@163.com+86 183 7523 6995

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026