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A real-world study of the efficacy and safety of hexapopal in ovarian cancer patients with thrombocytopenia due to PARP inhibitors

A real-world study of the efficacy and safety of hexapopal in ovarian cancer patients with thrombocytopenia due to PARP inhibitors

Status
Recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500102795
Enrollment
Unknown
Registered
2025-05-20
Start date
2025-05-31
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

epithelial ovarian cancer, fallopian tube cancer or primary peritoneal cancer

Interventions

Herombopag treatment group:NA

Sponsors

The First Affiliated Hospital of Xi'an Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients with epithelial ovarian cancer, fallopian tube cancer or primary peritoneal cancer confirmed by histopathology; 2. Age: 18-75 years old; 3. ECOG score: 0-2; 4. Being treated with PARP inhibitors: PARP inhibitor combined with chemotherapy regimen, PARP inhibitor combined with bevacizumab; 5. Occurrence PLT<100×10^9/L; 6. Normal function of major organs; 7. The researchers determined that patients could be treated with hexapopal.

Exclusion criteria

Exclusion criteria: 1. The patient is undergoing an intervention study; 2. Failure to understand the nature of the research or to obtain informed consent; 3. Other situations deemed unsuitable for inclusion in the study by the researcher;

Design outcomes

Secondary

MeasureTime frame
Proportion of patients with PARP reduction or suspension;Changes in PAPR Adjustment Volume;

Primary

MeasureTime frame
Proportion of responding patients;

Countries

China

Contacts

Public ContactLi Qiling

The First Affiliated Hospital of Xi'an Jiaotong University

liqiling@mail.xjtu.edu.cn+86 29 85323849

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026