vulvar lichen sclerosus
Conditions
Interventions
Mometasone furoate treatment group:Local treatment with 0.1% mometasone furoate cream: once daily in the first month, and once every other day in the next month until the end of follow-up
Tacrolimus treatment group:Local treatment with 0.1% tacrolimus cream: once daily in the first month, and once every other day in the next month until the end of follow-up
Sponsors
Obstetrics and Gynecology Hospital of Fudan University
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients admitted to the Obstetrics and Gynecology Hospital of Fudan University between December 1, 2022 and December 31, 2024 with a diagnosis of VLS based on typical clinical signs and symptoms or histopathological examination.Complete clinical data.
Exclusion criteria
Exclusion criteria: Participants who received topical or systemic glucocorticoid or immunosuppressive therapy within 4 weeks prior to study participation Patients diagnosed with vulvar intraepithelial neoplasia or vulvar squamous cell carcinoma People with serious underlying diseases, including diabetes, heart, liver, and renal insufficiency, malignant tumors, and acquired immune deficiency syndrome Allergic to the investigational drug Pregnancy, lactation or family planning Poor mental condition, unable to cooperate with researchers Any ineligibility for inclusion in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Score of Prutitus; | — |
Secondary
| Measure | Time frame |
|---|---|
| Skin color of vulva;Skin elasticity of vulva; | — |
Countries
China
Contacts
Public ContactQing Cong
Obstetrics and Gynecology Hospital of Fudan University
Outcome results
None listed