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Mechanism of ClC-3 regulating extracellular vesicle mediated cellular microenvironment to promote invasion of ectopic endometrial stromal cells

Mechanism of ClC-3 regulating extracellular vesicle mediated cellular microenvironment to promote invasion of ectopic endometrial stromal cells

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500102763
Enrollment
Unknown
Registered
2025-05-20
Start date
2025-05-31
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriosis

Interventions

Normal endometrial tissue in non EMs patients:NA
EMs patient in situ tissue:NA
Ectopic tissue in EMs patients:NA

Sponsors

The First Affiliated Hospital of Ningbo University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1: Patients diagnosed with endometriosis through pathology; 2: Age 18 and above; 3: The patient voluntarily participated in this study and signed an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Combine patients with other malignant tumors; 2.Patients with severe heart, liver, and kidney dysfunction; 3.Individuals with a history of mental illness or cognitive impairment who are unable to understand the research content and sign informed consent form patient; 4. Patients who are currently participating in other clinical trials that may affect the results of this study; 5. Pregnant or lactating women.

Design outcomes

Primary

MeasureTime frame
Differences in ER ß and ClC-3 levels;

Secondary

MeasureTime frame
ClC-3 affects the expression of extracellular vesicle CD9 in endometrial cells;

Countries

China

Contacts

Public ContactGuan Yutao

The First Affiliated Hospital of Ningbo University

2309732100@qq.com+86 135 6603 6278

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026