Schizophrenia
Conditions
Interventions
HD-tDCS stimulation + CCRT group:Conduct active HD-tDCS stimulation with a current intensity of 2mA,once a day for a total of 20 sessions.Engage in CCRT,once a day for a total of 20 sessions.
HD-tDCS stimulation group:Conduct active HD-tDCS stimulation with a current intensity of 2mA,once a day for a total of 20 sessions.
CCRT group:Engage in CCRT,once a day for a total of 20 sessions.
Control group:Maintain daily medication without intervention of HD-tDCS and CCRT.
Sponsors
The Second Affiliated Hospital of Xinxiang Medical University.
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Meets the clinical diagnostic criteria for schizophrenia according to DSM-5 for the current episode. 2. Patients who achieve a stable period through oral antipsychotic drug treatment are defined by the following criteria: a score of <= 5 on the items of delusion, hallucinatory behavior, exaggeration, and suspiciousness/victimization in the Positive and Negative Symptom Scale (PANSS), and a score of <= 4 on the PANSS conceptual disorganization. 3. Currently undergoing treatment with atypical antipsychotic medications, with equivalent doses of antipsychotic drugs calculated using the defined daily dose method. 4. Ages between 18-55 years 5. Educational level at the primary school level or above, capable of understanding and cooperating to complete the experiment.
Exclusion criteria
Exclusion criteria: 1. Patients are in the acute phase of the disease and cannot cooperate in completing the examination and operational tasks under guidance. 2. There are organic brain lesions, intellectual disabilities, or other severe physical illnesses. 3. Currently undergoing other neurostimulation therapies or evidence-based psychotherapy. 4. There are indications related to contraindications for HD-tDCS 5. There are visual impairments or significant eye diseases, such as color blindness, color weakness, cataracts, etc. 6. severe anxiety, depression, or substance abuse. 7. pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MATRICS Consensus Cognitive Battery;Brief Psychiatric Rating Scale;Positive and Negative Syndrome Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical Global Impressions;Social Disability Screening Schedule;Schizophrenia Quality of Life Scale; Functional Magnetic Resonance Imaging;General Information Questionnaire; | — |
Countries
China
Contacts
Public ContactYange Wei
The Second Affiliated Hospital of Xinxiang Medical University.
Outcome results
None listed