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Epidemiological study of chronic kidney disease and emotional disease based on tryptophan metabolism

Epidemiological study of chronic kidney disease and emotional disease based on tryptophan metabolism

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500102729
Enrollment
Unknown
Registered
2025-05-19
Start date
2025-06-01
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Kidney Disease

Interventions

Chronic kidney disease combined with emotional disorders group:None

Sponsors

Southern Medical University Hospital of Integrated Traditional Chinese and Western Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >= 18 years old; 2. Meet the diagnostic criteria for CKD: chronic kidney disease (CKD): the diagnosis of CKD refers to the KDOQI criteria: the CKD population is defined as a decline in renal function or the presence of proteinuria. Decreased renal function is defined as glomerular filtration rate eGFR300mg/g for overt albuminuria. ACR of 30~299mg/g is called microalbuminuria and >300mg/g is considered as overt albuminuria. Blood creatinine was used to calculate eGFR, and the estimated glomerular filtration rate (eGFR) was calculated by the simplified MDRD formula: eGFR(mL/min/1.73m2)=175×(blood creatinine)-1.234×(age)-0.179(0.79, female). The unit of blood creatinine is mg/dL, and the unit of age is years.; 3.Patients who signed the informed consent form; 4.Subjects or their immediate family members were able to cooperate with the information, specimen collection and other study-related examinations; 5. Subjects or their immediate family members are able to read and correctly complete the assessment form;

Exclusion criteria

Exclusion criteria: Those with any of the following were excluded: 1.Combined with serious primary disease; 2. Combined with serious infections 3.Those who are pregnant or breastfeeding; 4.Those who have been diagnosed with major depression or suicidal tendency, and those who have other mental illnesses;

Design outcomes

Primary

MeasureTime frame
Indicators Related to Emotional Diseases;renal function;Urine micro-protein;

Secondary

MeasureTime frame
Indicators related to tryptophan metabolism;

Countries

China

Contacts

Public ContactLi Dongyu

Southern Medical University Hospital of Integrated Traditional Chinese and Western Medicine

422069737@qq.com+86 185 2008 8839

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026