Schizophrenia
Conditions
Interventions
Sponsors
Tianjin Anding Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Applicants must be between 18 and 65 years old (inclusive), regardless of gender; 2. Patients diagnosed with episodes of schizophrenia by the study physician in accordance with the Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) (DSM-5), with no limitation on the first episode or recurrence; 3. Patient's PANSS negative scale score>=20 points; 4. The patient's MCCB-T score < 40 points; 5. No change in schizophrenia medication regimen within 30 days prior to signing the informed consent form until the trial period; 6. Have certain listening, speaking, reading, writing and comprehension skills, and be able to complete the research scale; 7. According to the judgment of the study doctor, the subject understands the purpose and procedures of this study, is able to comply with the requirements of the study protocol and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. History of other psychiatric disorders, neurological diseases, or substance abuse, as determined by the investigator to potentially interfere with efficacy evaluation; 2. History of epileptic seizures or documented epileptic convulsions; 3. Presence of metallic implants in the skull or cardiac devices (e.g., pacemakers); 4. Diagnosed with organic brain diseases, or history of severe head trauma or cranial surgery; 5. Received intracranial electroconvulsive therapy (ECT) or other physical therapies (e.g., transcranial magnetic stimulation [TMS], transcranial electrical stimulation) within the past 30 days; 6. A score =3 on the suicide item of the 17-item Hamilton Depression Rating Scale (HAMD-17); 7. Currently pregnant, breastfeeding, or planning pregnancy during the trial period; 8. Concurrent participation in another interventional clinical trial; 9. Any other condition deemed by the investigator to be unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Negative symptom;Anxiety symptom;Quality of life;Adverse event;Sleep quality;Positive and Negative Syndrome;Resting-State Functional Magnetic Resonance Imaging;Depression symptom; | — |
Countries
China
Contacts
Public ContactShen Li
Tianjin Anding Hospital
Outcome results
None listed