Cervical Cancer
Conditions
Interventions
Vaccine group:None
Control group:None
Sponsors
National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1) Women aged 18–45 years; 2)Naturally infected with HPV genotype 16, 18, 31, 33, 45, 52, or 58; 3) In the vaccine group: participants must have received HPV vaccination, and the infecting HPV genotype must be covered by the vaccine; 4) In the control group: participants must not have received any HPV vaccine prior to enrollment; 5) HPV genotypes must be matched between the two groups (i.e., overlapping genotypes covered by the vaccine); 6) Written informed consent obtained from all participants.
Exclusion criteria
Exclusion criteria: Refuse to participate in the research
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HPV genotyping;HPV DNA sequencing; | — |
Secondary
| Measure | Time frame |
|---|---|
| Antibody levels;Cellular immunity levels; | — |
Countries
China
Contacts
Public ContactFanghui Zhao
National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Outcome results
None listed