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Effect of Ciprofol on emergence agitation after tonsillectomy and adenoidectomy in children: a randomised controlled trial

Effect of Ciprofol on emergence agitation after tonsillectomy and adenoidectomy in children: a randomised controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500102708
Enrollment
Unknown
Registered
2025-05-19
Start date
2025-05-27
Completion date
Unknown
Last updated
2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

emergence agitation

Interventions

group H:Thirty minutes before the end of surgery, group H was administered ciprofol 0.2 mg/kg.
group C:Thirty minutes before the end of the surgery, Group C was administered 0.2 mg/kg of normal saline.

Sponsors

The Third Affiliated Hospital of Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 8 Years

Inclusion criteria

Inclusion criteria: 1. Age 3-8 years; 2. No gender restriction; 3. Weight 12~30 kg; 4. BMI 18~24 kg/m²; 5. ASA classification I~II; 6. Children scheduled for tonsil low-temperature plasma radiofrequency ablation + adenoid low-temperature plasma surgery under nasal endoscopy.

Exclusion criteria

Exclusion criteria: 1. Recent upper respiratory tract infection; 2. Difficult airway identified during preoperative evaluation; 3. Comorbid dysfunction of vital organs including heart, lungs, brain, liver, and kidneys; 4. Presence of developmental delay; 5. Accompanied by agitation disorder; 6. Existence of cognitive communication impairment; 7. Withdrawal from the study.

Design outcomes

Primary

MeasureTime frame
Postoperative agitation incidence rate;

Secondary

MeasureTime frame
Extubation time;heart rate;mean arterial pressure;Number of adverse reactions;

Countries

China

Contacts

Public ContactWei Xiaoyong

The Third Affiliated Hospital of Zhengzhou University

38774209@qq.com+86 139 3859 3029

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026