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Effects of different intensity isometric exercises of extremities on cardiovascular and muscle fitness in older adults with hypertension

Effects of different intensity isometric exercises of extremities on cardiovascular and muscle fitness in older adults with hypertension

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500102691
Enrollment
Unknown
Registered
2025-05-19
Start date
2025-05-20
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension in old age

Interventions

LL-IRT group:Exercise intensity: 30% MVC
HS-IRT group:Exercise intensity: 60% MVC
Control group:Keep the original lifestyle unchanged and do not carry out IRT intervention

Sponsors

Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) Age>=60 years; (2) Meet the diagnostic criteria for hypertension grade 1: without the use of antihypertensive drugs, blood pressure is measured 3 times on the same day, systolic blood pressure (SBP) is 140~159mmHg and/or diastolic blood pressure (DBP) is 90~99mmHg, hypertension has been clearly diagnosed and is receiving antihypertensive medication, although the blood pressure < 140/90mmHg, it should also be diagnosed as hypertension grade 1; (3) Have the ability to move independently, and be able to carry out resistance movement independently; Informed consent, voluntary participation in this study.

Exclusion criteria

Exclusion criteria: (1) Secondary hypertension; (2) Are using drugs that affect blood pressure in addition to antihypertensive drugs: such as glucocorticoids, sympathomimetic drugs, etc.; (3) Connective tissue disease (Marfan syndrome), thoracic aortic disease, history of pacemaker implantation and arrhythmia, heart failure or damage to important organ function, vasovagal syncope; (4) History of knee, hip, pelvis or femur fracture in the past 6 months; History of severe falls in the past 6 months; Major surgery in the past 6 months; (5) Participated in an organized training program in the past 6 months.

Design outcomes

Primary

MeasureTime frame
Clinical blood pressure;Heart rate variability;Aortic pulse wave velocity;Lower limb knee extensor muscle strength, knee flexion muscle strength, hip extension muscle strength;Muscle endurance (30-second seat standing);Muscle mass of both lower extremities;

Secondary

MeasureTime frame
Percentage of blood pressure reaching the target;Compliance;

Countries

China

Contacts

Public ContactHongyan Meng

Soochow University

menghongyan@suda.edu.cn+86 151 0620 0578

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026