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Evaluation of caries prevention effect of a novel fluoride toothpaste in children with different caries activity

Evaluation of caries prevention effect of a novel fluoride toothpaste in children with different caries activity

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500102686
Enrollment
Unknown
Registered
2025-05-19
Start date
2025-06-01
Completion date
Unknown
Last updated
2026-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Caries

Interventions

Control group:A 500-550ppm fluoride toothpaste was distributed to children, and the other interventions were the same as those in the trial group.
Experimental group:Subjects will use a uniformly distributed children's toothbrush and 950-1000ppm children's fluoride toothpaste to brush their teeth twice a day, respectively, after breakfast under

Sponsors

Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 7 Years

Inclusion criteria

Inclusion criteria: 1. Parental informed consent; 2. At baseline, 3-7 years old; 3. Can cooperate in determining caries activity; 4. Can complete follow-up within 12 months;

Exclusion criteria

Exclusion criteria: 1. Unable to complete follow-up due to serious illness; 2. Have taken antibiotics within one month; 3. Have taken hormones or immunosuppressants within 6 months; 4. History of local oral medication within one month; 5. Researchers believe that other diseases or conditions may affect the test results.

Design outcomes

Primary

MeasureTime frame
DMF index;

Countries

China

Contacts

Public ContactZhang Yu

Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine

zy24ymjulia@163.com+86 21 5331 5327

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 22, 2026