coronary artery disease(CAD)
Conditions
Interventions
control group:Use etomidate for anesthesia induction
Experimental group:Use remimazolam for anesthesia induction
Sponsors
Beijing Anzhen Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age between 18-70 years old, gender not restricted; 2. American Society of Anesthesiologists (ASA) physical status classification ?-?; 3. Scheduled for intermediate- to high-risk non-cardiac surgery; 4. Voluntarily agree to participate in the study and sign the informed consent form
Exclusion criteria
Exclusion criteria: Patients who are known to be allergic to remimazolam or have a history of severe allergies and a family history of allergies; Patients who are known to be allergic to etomidate; Patients who have long-term used narcotic analgesics, sedatives or non-steroidal anti-inflammatory drugs; Patients with opioid dependence or opioid tolerance; Patients with severe abnormalities in lung, liver and kidney functions and those with low adrenal cortical function; Patients with epilepsy;Patients with severe arrhythmia; Patients with acute myocardial infarction; Emergency surgery; Patients whom the researchers consider unsuitable to participate in this clinical study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood pressure;heart rate;bispectral index;height;weight; | — |
Countries
China
Contacts
Public ContactJun Ma
Beijing Anzhen Hospital, Capital Medical University
Outcome results
None listed