Ischemic stroke
Conditions
Interventions
iTBS group:Cerebellar Intermittent ?-Burst stimulation (Real)
Sham group:Cerebellar Intermittent ?-Burst stimulation (Sham)
Sponsors
Xuanwu Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Age 18-75 years old; Gender is not limited; MRI scan confirmed supratentorial, subcortical and unilateral focal ischemic stroke. First symptomatic ischemic stroke with a duration of 14 +/- 2 days; Right handed; 48h after stroke, the NIHSS score was less than 16 and the sixth item score was not 0; Patients themselves and/or their legal guardians agreed to participate in this clinical study and signed an informed consent form.
Exclusion criteria
Exclusion criteria: Contraindications to TMS and MRI (e.g. intracranial or subcortical metallic implants, except non-ferromagnetic dental implants); Claustrophobia; Epilepsy, aphasia or cognitive impairment that severely impairs communication; The patient had been bedridden for more than 2 months before the onset of the disease. Patients received transcranial magnetic stimulation within the past 3 months; He had a history of severe hearing impairment and alcohol dependence.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Berg Balance Score, BBS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Spatio-temporal parameters of gait, plantar pressure and balance evaluated based on sensors;Fugl-Meyer score, FMA;Functional ambulation category scale, FAC;Barthel index, BI;Rates of Independent walking;Time-frequency-space indicators of brain function (TMS-EEG; fMRI; DTI; sMRI); | — |
Countries
China
Contacts
Public ContactCao Lei
Xuanwu Hospital, Capital Medical University
Outcome results
None listed