Diabetes mellitus
Conditions
Interventions
Continuing smoking Group:None
Smoking cessation Group:None
Sponsors
The First People's Hospital of Tai 'an
Eligibility
Sex/Gender
All
Age
40 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Subjects aged 40-65 years old; 2.The fasting blood glucose is >=7.0 mmol/L, or the 2-hour postprandial blood glucose is>=11.1mmol/L; 3.Regular physical examination and laboratory tests show normal renal and liver function and acceptable lipid profile; 4.Regular cigarette smoking for at least 10 years on average 10 cigarettes or more/day during the preceding year; 5.For patients in the group of smoking cessation, they should meet the criteria mentioned above for cigarette smoking and agree to stop smoking for at least 90 days; 6.Voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Body mass index>=30kg/m^2; 2.Blood pressure>=140/90; 3.Fasting serum triglyceride >=400mg/dl; 4.Take statin within 3 months preceding blood sampling; 5.Those with severe heart, liver, kidney or thyroid diseases, severe infections, as well as stress conditions such as tumors, trauma, surgery and burns; 6.Any concomitant illness or mental condition that could interfere with the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma total cholesterol ;Plasma high-density lipoprotein cholesterol;Plasma low-density lipoprotein cholesterol;Triglyceride;Apolipoprotein A1;Apolipoprotein B;Malondialdehyde;Super oxygen dehydrogenises activity;Tumor necrosis factor-alpha ;Interleukin-6;Paraoxonase-1 activity;HDL function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Plasma glucose level;Lipoprotein a ;Hypersensitive C-reactive protein ;Urinary cotinine; | — |
Countries
China
Contacts
Public ContactYun Lijun
The First People's Hospital of Tai 'an
Outcome results
None listed