Disc Herniation
Conditions
Interventions
Pulse radiofrequency group (Group R):Only perform blunt needle pulsed radiofrequency treatment
Collagenase group (Group C):Only perform blunt needle collagenase injection
Combined group (R + C group):Pulsed radiofrequency followed by collagenase injection
Sponsors
The Second Affiliated Hospital of Xiamen Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Age 18-70 years Single-level cervical or lumbar disc herniation MRI/CT-confirmed disc protrusion consistent with clinical symptoms
Exclusion criteria
Exclusion criteria: Intervertebral disc calcification, bony spinal canal stenosis, spinal instability or cauda equina syndrome. Coagulation dysfunction, infection, pregnancy, history of collagenase allergy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale;MacNab efficacy grading; | — |
Secondary
| Measure | Time frame |
|---|---|
| Area reduction rate of protrusions;Intervertebral disc height variation;Neck Disability Index;Oswestry Disability Index;Incidence rate of adverse events;Complications related to collagenase; | — |
Countries
China
Contacts
Public ContactZhang Guanghui
The Second Affiliated Hospital of Xiamen Medical University
Outcome results
None listed