Gastrointestinal malignancy
Conditions
Interventions
Normal hemoglobin concentration group:None
Tumors cause mild anemia group:None
Tumors cause moderate anemia group:None
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 65 to 80 years; 2. ASA classification level III; 3. Patients undergoing scheduled laparoscopic gastrointestinal tumor surgery.
Exclusion criteria
Exclusion criteria: 1. illiteracy or those who are unable to cooperate due to audio-visual impairments; 2. Patients with concurrent neurological diseases (abnormal mental state, consciousness) or other major diseases (such as coronary heart disease, etc.); 3. Previous use of psychotropic drugs or sedatives; 4. Previous heavy alcoholics (> 40g/d for men and > 20g/d for women); 5. Those who already have cognitive impairment before the operation; 6. Patients who have previously undergone tests related to cognitive function; 7. Those who undergo radiotherapy or chemotherapy before the operation; 8. Patients who need a large amount of blood transfusion during the operation due to their condition.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mini-Mental State Examination;Montreal Cognitive Assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory factor TNF-a in plasma;Inflammatory factor IL-6 in plasma;Brain injury marker S100ß; | — |
Countries
China
Contacts
Public ContactMin Jia
The First Affiliated Hospital of Nanchang University
Outcome results
None listed