A multicenter prospective cohort study of oral Staphylococcus and Neisseria Tablets in stable patients with bronchiectasis

Status

Recruiting

Phases

Phase 4

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2500102639

Enrollment

Unknown

Registered

2025-05-16

Start date

2023-01-10

Completion date

Unknown

Last updated

2025-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bronchiectasis

Interventions

observation group:None

control group:None

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. 18-80 years old; 2. Idiopathic or postinfectious bronchiectasis; 3. stable period; 4. 1 month after acute exacerbation; 5. There were more than 2 acute exacerbations within 1 year before enrollment.

Exclusion criteria

Exclusion criteria: 1. Bronchiectasis of specific etiology; 2. Smoking; 3. combined with bronchial asthma; 4. serious heart, liver, kidney, nervous system diseases; 5. Allergic to Nefella albicans tablets.

Design outcomes

Primary

Measure	Time frame
Number of acute exacerbations;	—

Secondary

Measure	Time frame
Rate of hospitalization;Complement 3;Complement 4;CD4 T lymphocyte absolute count;Sputum volume;Forced vital capacity;Leicester Cough Questionnaire;Immunoglobulin G;Immunoglobulin A;Immunoglobulin M;sputum properties;sputum culture;CD8 T lymphocyte absolute count;Forced expiratory volume in one second;	—

Countries

China

Contacts

Public ContactLi Yu

Qilu Hospital of Shandong University

qlliyures@163.com+86 185 6008 2770

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026