Stroke
Conditions
Interventions
tDCS+rTMS:rTMS: an octagonal coil with the center aligned with the left dorsolateral prefrontal cortex, at a 45 degree angle to the skull, at a frequency of 10 Hz, with a stimulation intensity of 80%
tDCS: Left dorsolateral prefrontal cortex 1.5mA intensity, 40Hz, 10ms pulse, 5 pulses, each 500Hz, pulse width 1ms, pulse interval of 1ms in constant current mode, 5 times a week, continuous stimulati
tDCS+rTMS-sham:tDCS: Left dorsolateral prefrontal cortex 1.5mA intensity, 40Hz, 10ms pulse, 5 pulses, each 500Hz, pulse width 1ms, pulse interval of 1ms in constant current mode, 5 times a week, conti
rTMS-sham: The coil is set at a 90 degree angle to the skull, with all other settings remaining the same.
tDCS-sham+rTMS:tDCS: The current increases from 3 seconds to 1.5 mA, maintains for 30 seconds, and then slowly decreases to 0 mA, with the remaining settings remaining the same
rTMS: an octagonal coil with the center aligned with the left dorsolateral prefrontal cortex, at a 45 degree angle to the skull, at a frequency of 10 Hz, with a stimulation intensity of 80% of the res
tDCS-sham+rTMS-sham:tDCS: The current increases from 3 seconds to 1.5 mA, maintains for 30 seconds, and then slowly decreases to 0 mA, with the remaining settings remaining the same
Sponsors
Beijing Rehabilitation Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1 Patients who meet the diagnostic criteria for stroke, are diagnosed by cranial CT or MRI, are the first case, and have a onset time of = 2 weeks andStage I; 5 Patients can understand and actively participate in the evaluation plan, and patients and their families agree and sign the 'informed consent form'.
Exclusion criteria
Exclusion criteria: 1 Individuals with unstable vital signs; 2 Patients with severe diseases such as respiratory failure, heart failure, renal failure, and tumors, as well as those with bipolar affective disorder before stroke; 3 Individuals who have difficulty cooperating due to symptoms such as aphasia or forgetfulness, and have communication barriers; 4 Diagnosed with severe depression through the Hospital Anxiety and Depression Scale; 5 Individuals with a history of mental illness or taking antipsychotic medication; 6 Have a history of epileptic seizures; 7 Patients who have undergone cranial surgery; 8 Contraindications for receiving magnetic resonance imaging or transcranial magnetic stimulation or transcranial direct current stimulation (cardiac pacemaker, such as after DBS surgery).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Depression Rating Scale;Hamilton Anxiety Rating Scale;Beck Depression Scale;Beck Anxiety Scale;Pittsburgh Sleep Quality Index;Hospital Anxiety and Depression Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Functional Independence Assessment Scale;Improved Barthel Index;Sleep Quality Scale;Resting State Functional Magnetic Resonance Study; | — |
Countries
China
Contacts
Public ContactPeiling Huang
Beijing Rehabilitation Hospital Affiliated to Capital Medical University
Outcome results
None listed