Squamous Cell Carcinoma of the Head and Neck
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Case group: 1. Clinical diagnosis of head and neck squamous cell carcinoma or radiation-induced osteomyelitis of the jawbone caused by secondary infection after radiotherapy; 2. Complete clinical examination data and demographic information; 3. The lifestyle habits survey questionnaire is complete; 4. Can tolerate prolonged oral operation; Control group: 1. Clinical diagnosis is not head and neck squamous cell carcinoma or bone marrow infection caused by secondary infection after radiotherapy; 2. Complete clinical examination data or demographic information; 3.The lifestyle habits survey questionnaire is complete; 4. Can tolerate prolonged oral operation;
Exclusion criteria
Exclusion criteria: Case group: 1. Under 18 years old; 2. Human immunodeficiency virus infection or drug addiction; 3. Suffering from digestive or respiratory diseases in the past six months; 4. Patients who refuse or do not cooperate with gas collection. Control group: 1. Under 18 years old; 2. Human immunodeficiency virus (HIV) infection or drug addiction; 3. Suffering from digestive or respiratory diseases in the past six months; 4. Patients who refuse or do not cooperate with gas collection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composition of oral gases;16S rDNA sequencing analysis of the lesion;Metabolomics analysis of the lesion; | — |
Countries
China
Contacts
Hospital of Stomatology, Sun Yat-sen University