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Efficacy and Immunological Analysis of Lingnan Painless Bee Therapy and Acupuncture in Treating Allergic Rhinitis

Efficacy and Immunological Analysis of Lingnan Painless Bee Therapy and Acupuncture in Treating Allergic Rhinitis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500102603
Enrollment
Unknown
Registered
2025-05-16
Start date
2025-08-15
Completion date
Unknown
Last updated
2025-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

allergic rhinitis

Interventions

Acupuncture Group:acupuncture
Sham Acupuncture Group:sham acupuncture

Sponsors

The Fifth Affiliated Hospital of Guangzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Age >=18 years and <=60 years, gender unrestricted, with a history of rhinitis allergy for 3 months or more; 2. Voluntarily participate and sign an informed consent form; 3. Meet the diagnostic criteria for allergic rhinitis in both Western and Chinese medicine; 4. Participants are willing to stop using current decongestants and anti-allergy medications as instructed, starting from the washout period before the trial (2 weeks prior to the experiment) and throughout the trial; 5. No symptoms of acute respiratory infection in the two weeks prior to enrollment.

Exclusion criteria

Exclusion criteria: 1. Individuals with a positive bee venom skin allergy test or positive bee venom allergen test (bee sting therapy group); 2. Individuals afraid of bee stings (bee sting group and combination group), afraid of acupuncture (acupuncture group and combination group), or allergic to alcohol; 3. Individuals with a positive urine pregnancy test or pregnant women; 4. Those with a history of alcoholism, mental disorders, epilepsy, or severe cognitive impairment; 5. Individuals with serious diseases, such as uncontrolled hypertension, insulin-dependent diabetes, past or present malignant tumors, severe dyslipidemia, liver or kidney dysfunction, anemia, active pulmonary tuberculosis, or other infectious or systemic diseases; 6. Individuals with congenital nasal deformities, including nasal dermoid cysts, congenital midline nasal masses, sinusitis, asthma, or nasal septum deviation; 7. Individuals with severe bronchial asthma (meeting the diagnostic criteria for severe bronchial asthma according to the 2020 Guidelines for the Prevention and Treatment of Bronchial Asthma); 8. Individuals who have participated in clinical studies involving various drugs, devices, or other interventions in the past 3 months.

Design outcomes

Primary

MeasureTime frame
Total immunoglobulin E;Immunoglobulin G;Interleukin-4;Interleukin-6;IFN-?;

Secondary

MeasureTime frame
Visual Analogue Scale (VAS);Total Nasal Symptom Score (TNSS);Total Non-Nasal Symptom Score (TNNSS);(Rhinoconjunctivitis Quality of Life Questionnaire,RQLQ);

Countries

China

Contacts

Public ContactHongbo Wu

The Fifth Affiliated Hospital of Guangzhou Medical University

wuhongbo@gzhmu.edu.cn+86 159 0203 2912

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026