allergic rhinitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age >=18 years and <=60 years, gender unrestricted, with a history of rhinitis allergy for 3 months or more; 2. Voluntarily participate and sign an informed consent form; 3. Meet the diagnostic criteria for allergic rhinitis in both Western and Chinese medicine; 4. Participants are willing to stop using current decongestants and anti-allergy medications as instructed, starting from the washout period before the trial (2 weeks prior to the experiment) and throughout the trial; 5. No symptoms of acute respiratory infection in the two weeks prior to enrollment.
Exclusion criteria
Exclusion criteria: 1. Individuals with a positive bee venom skin allergy test or positive bee venom allergen test (bee sting therapy group); 2. Individuals afraid of bee stings (bee sting group and combination group), afraid of acupuncture (acupuncture group and combination group), or allergic to alcohol; 3. Individuals with a positive urine pregnancy test or pregnant women; 4. Those with a history of alcoholism, mental disorders, epilepsy, or severe cognitive impairment; 5. Individuals with serious diseases, such as uncontrolled hypertension, insulin-dependent diabetes, past or present malignant tumors, severe dyslipidemia, liver or kidney dysfunction, anemia, active pulmonary tuberculosis, or other infectious or systemic diseases; 6. Individuals with congenital nasal deformities, including nasal dermoid cysts, congenital midline nasal masses, sinusitis, asthma, or nasal septum deviation; 7. Individuals with severe bronchial asthma (meeting the diagnostic criteria for severe bronchial asthma according to the 2020 Guidelines for the Prevention and Treatment of Bronchial Asthma); 8. Individuals who have participated in clinical studies involving various drugs, devices, or other interventions in the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total immunoglobulin E;Immunoglobulin G;Interleukin-4;Interleukin-6;IFN-?; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale (VAS);Total Nasal Symptom Score (TNSS);Total Non-Nasal Symptom Score (TNNSS);(Rhinoconjunctivitis Quality of Life Questionnaire,RQLQ); | — |
Countries
China
Contacts
The Fifth Affiliated Hospital of Guangzhou Medical University