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Effect of ultrasound-guided anterior approach sacral plexus block on catheter-related bladder discomfort after transurethral prostatectomy

Effect of ultrasound-guided anterior approach sacral plexus block on catheter-related bladder discomfort after transurethral prostatectomy: A double-blind, randomized, placebo-controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500102595
Enrollment
Unknown
Registered
2025-05-16
Start date
2025-05-22
Completion date
Unknown
Last updated
2025-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

regional block

Interventions

Ropivacaine blockade group:Anterior approach sacral plexus block with 0.25% ropivacaine
Normal saline control group:Normal saline anterior approach sacral plexus infiltration

Sponsors

Beijing Chaoyang Hospital Affiliated to Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients who have signed the informed consent form and voluntarily joined the study, scheduled for elective transurethral prostatectomy under general anesthesia, aged 50 - 80 years, with a body mass index (BMI) of 18 - 35 kg/m² and an American Society of Anesthesiologists (ASA) physical status classification of Class I to III.

Exclusion criteria

Exclusion criteria: Patients with prostate cancer, severe urinary tract infection, or a diagnosis of overactive bladder or neurogenic bladder; those who have received treatment with M-receptor antagonists or ß3-adrenergic receptor agonists within the past two weeks; those with a preoperative suprapubic catheter in place; individuals with a history of prostate or bladder neck surgery; patients with a known allergy to ropivacaine or any other local anesthetic; cases with infection at the puncture site; individuals with coagulopathy; patients with severe hepatic or renal dysfunction; those on long-term opioid therapy; and patients with psychiatric disorders or language barriers will be excluded from the study.

Design outcomes

Primary

MeasureTime frame
Incidence of moderate to severe catheter-related bladder discomfort (CRBD) within 24 hours postoperatively.;

Secondary

MeasureTime frame
Incidence of catheter-related bladder discomfort;CRBD score;Pain score;Incidence of agitation during the recovery period.;consumption of intravenous morphine equivalent after surgery;need for rescue analgesic within 24h after surgery;time to first ambulation;QoR-15 score at 24h after surgery; patient satisfaction;length of stay after surgery;

Countries

China

Contacts

Public ContactWu Anshi

Beijing Chaoyang Hospital Affiliated to Capital Medical University

wuanshi1965@163.com+86 135 1101 0883

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 4, 2026