Hemifacial spasm
Conditions
Interventions
Gold Standard:Based on the national-level planning textbook for higher education 'Neurology' (5th edition, edited by Wang Weizhi, People's Health Publishing House), it is proposed that: 1. The onset i
2. The spasms often start from the orbicularis oculi and may spread to the facial muscles, orbicularis oris, and even the neck muscles
3. The severity of the spasms varies, worsens with stress and fatigue, stops upon falling asleep, and cannot be controlled voluntarily
4. There are no positive signs in the nervous system, and head CT and MRI exclude tumors and other diseases.
Index test:Musculoskeletal Ultrasound (Model: uSmart3300, Terason Ultrasound Imaging System Version: 5.11.4, Frequency: 3-17Hz) - Collecting facial anatomical information
Biomedical Signal Acquisition
Sponsors
Huazhong University of Science and Technology Union Shenzhen Hospital ,Rehabilitation Medicine Department
Eligibility
Sex/Gender
All
Age
20 Years to 90 Years
Inclusion criteria
Inclusion criteria: Healthy subjects: Matched with patients in terms of age, gender, and education, with no history of head trauma, no history of mental or neurological diseases, no physical activity disorders, and no factors affecting them prior to participation such as infections, fatigue, or emotional agitation. Participants must sign an informed consent form. Patients with facial muscle spasms: 1. Must meet the following diagnostic criteria; 2. No gender restrictions, age: primarily between 18 to 75 years, based on actual recruitment needs; 3. Course of disease: primarily within 1 week to 2 years, with some cases from 7 months to 9 years, and 2 months to 20 years, based on actual needs; 4. Must voluntarily join this research trial, demonstrate good compliance, and either the patient or their family must sign an informed consent form; 5. Patients must have a good mental state and be able to communicate normally; 6. Approved by the hospital's ethics committee.
Exclusion criteria
Exclusion criteria: 1.Other facial movement disorders such as blepharospasm, facial tics, myoclonus, oromandibular dystonia, etc.; 2.Individuals who have not received any other treatment methods or medication during the course of treatment; 3.Secondary hemifacial spasm patients with clear causes such as vascular malformations, arteriovenous malformations, aneurysms, etc.; 4.Patients with a history of allergy to the study drug or with coagulation disorders; 5.Patients with severe heart, liver, kidney, or other diseases, as well as pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Musculoskeletal ultrasound;Neuroelectrophysiology;Blood perfusion; | — |
Countries
China
Contacts
Public ContactSui Minghong
Huazhong University of Science and Technology Union Shenzhen Hospital ,Rehabilitation Medicine Department
Outcome results
None listed