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The effect of intraoperative local infiltration analgesia+/- postoperative adductor canal block on analgesia after total knee arthroplasty

The effect of intraoperative local infiltration analgesia+/- postoperative adductor canal block on analgesia after total knee arthroplasty

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500102583
Enrollment
Unknown
Registered
2025-05-16
Start date
2024-04-23
Completion date
Unknown
Last updated
2025-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Treatment group:local infiltration analgesia (LIA) during total knee arthroplasty (TKA) add adductor canal block (ACB) after TKA
Control group:local infiltration analgesia (LIA) during total knee arthroplasty (TKA)

Sponsors

The University of Hongkong - Shenzhen Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Planned for unilateral total knee arthroplasty using epidural anesthesia; 2.American Society of Anesthesiologists Physical Status (ASA PS) grades I-III; 3.Aged between 60-80 years; 4.Body Mass Index (BMI) between 18-40;

Exclusion criteria

Exclusion criteria: 1.Pathological diseases other than osteoarthritis of the knee (such as rheumatoid arthritis, traumatic arthritis, and septic arthritis); 2.Knee flexion deformity exceeding 30 degrees; varus or valgus deformity exceeding 30 degrees; 3.Unable to walk without the aid of assistive devices prior to surgery; 4.History of open knee surgery or treatment for knee infection; 5.Knee revision surgery; 6.Bilateral knee replacement; 7.Lack of communication ability; 8.Neuropathic pain or sensory disturbances in the surgical limb; 9.Known allergy to study drugs; 10.Varicose, skin lesions, scars, etc., at the site of adductor canal injection; 11.Chronic use of opioids, with a daily oral morphine milligram equivalent (MME) dose exceeding 30 mg;

Design outcomes

Primary

MeasureTime frame
Cumulative morphine consumption within 48 hours post-TKA surgery;

Secondary

MeasureTime frame
VAS scores;Timed Up and Go test (TUG);The rate of complications;

Countries

China

Contacts

Public ContactZhu Qi

The University of Hongkong - Shenzhen Hospital

zhuq@hku-szh.org+86 755 86913333

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026