Trigeminal neuralgia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Meet the International Classification of Headache Disorders (ICHD-3) diagnostic criteria for ITN and CTN; Age of patients > 18 years old, < 75 years old; Right-handed; Unilateral pain in the trigeminal innervation area; Stinging or shock-like pain caused by the mouth and facial trigger area; No significant neurological disorders or sensory deficits were found after clinical evaluation.
Exclusion criteria
Exclusion criteria: STN confirmed by MR; Other types of pain disorders; Suffering from a major mental illness; In the past, she has performed craniocerebral surgery such as MVD. Patients with substance addiction; He has contraindications to MR Examination and cannot tolerate prolonged MR Examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| white matter diffusion parameters based on NODDI;the contents of GABA and Glx in the thalamus;fMRI functional connectivity parameters of pain-related brain regions; | — |
Secondary
| Measure | Time frame |
|---|---|
| visual analog scale scoring;mcgillPain questionnaire scoring;self-rating anxiety scale scoring;self-rating depression scale scoring; | — |
Countries
China
Contacts
The Second Hospital & Clinical Medical School, Lanzhou University