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An Observational Study Comparing the Analgesic Efficacy of Liposomal Bupivacaine versus Ropivacaine Injection in Multimodal Postoperative Pain Management Following Laparoscopic Gastrointestinal Surgery

An Observational Study Comparing the Analgesic Efficacy of Liposomal Bupivacaine versus Ropivacaine Injection in Multimodal Postoperative Pain Management Following Laparoscopic Gastrointestinal Surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500102553
Enrollment
Unknown
Registered
2025-05-15
Start date
2025-05-19
Completion date
Unknown
Last updated
2025-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Interventions

Bupivacaine liposome group / Ropivacaine injection group:None

Sponsors

Peking University Cancer Hospital Inner Mongolia Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age>18 or<80 years old; 2. First surgery for gastric or colon cancer; 3. Agree to use intravenous analgesia pump after surgery.

Exclusion criteria

Exclusion criteria: 1.BMI28 kg/m ^ 2; 2. Allergies to bupivacaine liposomes, ropivacaine injection, or other anesthetic drugs used in this study; 3. Existence of cardiac dysfunction, including II-III degree atrioventricular block or atrial fibrillation; 4. Severe liver, kidney, brain, and lung diseases before surgery; 5. Patients who are unable to cooperate in completing the research plan, including those with language difficulties, infectious diseases, or conscious disorders; 6. History of chronic pain: headache, back pain, lower back pain, limb pain, gout history, spontaneous pain in Parkinson's disease; 7. Mental disorders caused by psychoactive substances or non addictive substances, organic mental disorders, and other mental disorders accompanying mental illnesses.

Design outcomes

Primary

MeasureTime frame
Pain visual analog scale at 4 hours, 24 hours, 48 hours, and 72 hours post-operation.;

Secondary

MeasureTime frame
Clinical evaluation indicators related to analgesia;Indicators related to side effects of analgesia;Perioperative hemodynamic data;The incidence and mortality rate of perioperative complications.;Post-operative drainage tube drainage volume and removal time;ICU occupancy rate and ICU duration;

Countries

China

Contacts

Public ContactLiu Yinghua

Peking University Cancer Hospital; Inner Mongolia Hospital, Peking University Cancer Hospital

13693605452@163.com+86 136 9360 5452

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026