Skip to content

Pharyngeal Spraying of Dexmedetomidine for Preventing Postoperative Sore Throat After Rigid Bronchoscopy: A Prospective, Dual-Center, Double-Blind, Randomized Controlled Trial

Pharyngeal Spraying of Dexmedetomidine for Preventing Postoperative Sore Throat After Rigid Bronchoscopy: A Prospective, Dual-Center, Double-Blind, Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500102549
Enrollment
Unknown
Registered
2025-05-15
Start date
2025-06-01
Completion date
Unknown
Last updated
2025-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Sore Throat

Interventions

Dexmedetomidine group:Following successful induction of anesthesia and prior to commencement of rigid bronchoscopy, bilateral vocal cord mucosa at the glottic region were uniformly administered dexmed
Normal saline group:Following anesthetic induction and preceding rigid bronchoscopy instrumentation, bilateral vocal cords at the glottic region were administered 0.9% sodium chloride solution (5 mL t

Sponsors

Shanghai Changhai Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Age range: 18-75 years old, gender not limited; 2. Patients who plan to undergo rigid bronchoscopy under general anesthesia; 3. ASA grades I-III; 4. Sign the informed consent form;

Exclusion criteria

Exclusion criteria: 1. Allergies to the drugs involved in this study; 2. Preoperative sore throat or respiratory tract infection in the past 2 weeks; 3. Patients with severe cardiovascular and neurological diseases, as well as liver and kidney dysfunction; 4. Pregnant or lactating women; 5. Have participated in or are currently participating in other clinical trials within the past month.

Design outcomes

Primary

MeasureTime frame
The incidence of moderate-to-severe postoperative sore throat (POST) within 24 hours following rigid bronchoscopy, defined as a modified POST score >=2.;

Secondary

MeasureTime frame
Postoperative modified POST score ;Duration of postoperative sore throat (modified POST score >= 2);Postoperative hoarseness level;

Countries

China

Contacts

Public ContactLulong Bo

Shanghai Changhai Hospital

bartbo@smmu.edu.cn+86 138 1728 3189

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026