perioperative neurocognitive disorders
Conditions
Interventions
Group Remimazolam :Using remimazolam for anesthesia induction and maintenance
Group Propofol:Using propofol for anesthesia induction and maintenance
Sponsors
Wuxi Second Renmin Hospital
Eligibility
Sex/Gender
Male
Age
65 Years to 100 Years
Inclusion criteria
Inclusion criteria: Elderly patients aged > 65 years who underwent laparoscopic radical prostatectomy ASA rating is I~II The estimated operation time is 1~3h
Exclusion criteria
Exclusion criteria: Benzodiazepine allergy Preoperative sleep disturbance MMSE < 27 points Preoperative opioid use History of alcoholism Significant renal or hepatic dysfunction Significant cardiopulmonary instability Has participated in other clinical trials Acute angular glaucoma Myasthenia gravis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Delirium Rating Scale, DRS-R-98;Montreal Cognitive Assessment; | — |
Countries
China
Contacts
Public ContactDongXiao Huang
Wuxi Second Renmin Hospital
Outcome results
None listed