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Mechanism of constipation promoting colon polyp formation through immune and inflammatory pathways

Mechanism of constipation promoting colon polyp formation through immune and inflammatory pathways

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500102541
Enrollment
Unknown
Registered
2025-05-15
Start date
2025-05-15
Completion date
Unknown
Last updated
2025-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colon polyp

Interventions

Observation group:None

Sponsors

The Second Hospital of Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1 Over 18 years old; 2 Completed colonoscopy; 3 Met the diagnostic criteria for constipation in Rome IV; 4 Those with complete preoperative general information, clinical pathological data, and imaging reports; 5 Had not received radiotherapy or chemotherapy before surgery.

Exclusion criteria

Exclusion criteria: 1 Patients with incomplete colonoscopy, pathological evidence of colorectal cancer, previous history of colorectal cancer, previous history of endoscopic polypectomy, inflammatory bowel disease, intestinal tuberculosis, Behcet's disease, familial adenomatous polyposis or other chronic colitis; 2 Those who are bedridden for a long time or have severe mental illness; 3 Those who do not cooperate with the investigation.

Design outcomes

Primary

MeasureTime frame
Inflammatory indicators;Colonic polyp data; Severity and classification of constipation;

Countries

China

Contacts

Public ContactLiu Lan

The Second Hospital of Shandong University

liulandoctor@163.com+86 176 6008 0708

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026